Altered Contralateral Sensorimotor System Organization after Experimental Hemispherectomy: A Structural and Functional Connectivity Study
نویسندگان
چکیده
منابع مشابه
Resting-state fMRI after experimental hemispherectomy in rats: changes in functional connectivity and network synchronization
Introduction Hemispherectomy is a last resort treatment for children with catastrophic hemispheric epilepsy. It abolishes seizures and improves quality of life. The remarkable motor recovery after hemispherectomy, observed in both clinical and experimental settings, reflects the plastic capacities of the brain, especially at young age. Direct cortical stimulation of the healthy hemisphere in ad...
متن کاملCorrespondence between altered functional and structural connectivity in the contralesional sensorimotor cortex after unilateral stroke in rats: a combined resting-state functional MRI and manganese-enhanced MRI study.
This study shows a significant correlation between functional connectivity, as measured with resting-state functional magnetic resonance imaging (MRI), and neuroanatomical connectivity, as measured with manganese-enhanced MRI, in rats at 10 weeks after unilateral stroke and in age-matched controls. Reduced interhemispheric functional connectivity between the contralesional primary motor cortex ...
متن کاملThe reorganization of sensorimotor function in children after hemispherectomy. A functional MRI and somatosensory evoked potential study.
Children who have suffered extensive unilateral brain injury early in life may show a remarkable degree of residual sensorimotor function. It is generally believed that this reflects the high capacity of the immature brain for cerebral reorganization. In this study, we investigated 17 patients who had undergone hemispherectomy for relief from seizures; eight of the patients had congenital brain...
متن کاملMeningioma after contralateral hemispherectomy for malignant glioma: case report.
A patient is described who successfully underwent cerebral hemispherectomy for malignant glioma and whose death nine months later, wrongly ascribed to recurrent malignancy, was in fact due to a subsequently-developing benign meningioma in the remaining hemisphere. The possible advantages of a modification of standard hemispherectomy technique are also discussed.
متن کاملRecovery of sensorimotor function after experimental stroke correlates with restoration of resting-state interhemispheric functional connectivity.
Despite the success of functional imaging to map changes in brain activation patterns after stroke, spatiotemporal dynamics of cerebral reorganization in correlation with behavioral recovery remain incompletely characterized. Here, we applied resting-state functional magnetic resonance imaging (rs-fMRI) together with behavioral testing to longitudinally assess functional connectivity within neu...
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ژورنال
عنوان ژورنال: Journal of Cerebral Blood Flow & Metabolism
سال: 2015
ISSN: 0271-678X,1559-7016
DOI: 10.1038/jcbfm.2015.101